Fig. 1 · Structure
Documents & Downloads
MMAF-OtBu
Modified MMAF
MMAF-OtBu is a modified derivative of MMAF, primarily utilized in the synthesis of antibody-drug conjugates (ADCs). This compound enhances the therapeutic potential of ADCs by providing improved stability and controlled release of cytotoxic agents. Its key biological activity supports targeted cancer treatments, making it a valuable reagent in cancer research and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 745017-95-2 |
| Applications | Modified MMAF |
| Formula | C43H73N5O8 |
| Molecular Weight | 788.07 |
| SMILES | CC(C)(C)OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](NC)C(C)C)=O)=O)=O)OC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.