Fig. 1 · Structure
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MMs02943764
Anticancer Compound
MMs02943764 is a 1,2,4-triazole derivative that exhibits potent anticancer activity. This compound demonstrates significant antiproliferative effects across various cancer cell lines, particularly noted for its cytotoxicity against the K562 leukemia cell line with an IC50 of 35.264 μM. MMs02943764 functions by inhibiting Mdm2 and Pirh2, thereby stabilizing p53 and inducing cell cycle arrest in K562 cells. This makes MMs02943764 a valuable tool for research in cancer therapy and cell cycle regulation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 708287-29-0 |
| Applications | Anticancer Compound |
| Formula | C24H25BrF2N4O2S |
| Molecular Weight | 551.45 |
| SMILES | O=C(CSC1=NN=C(COC2=CC(C)=CC=C2C(C)C)N1CC=C)NC3=C(Br)C=C(F)C=C3F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.