Fig. 1 · Structure
Documents & Downloads
MMV009085
PfHT1 Inhibitor
MMV009085 is a selective inhibitor of the Plasmodium falciparum hexose transporter (PfHT1), demonstrating potential as an anti-malarial agent. This compound significantly inhibits glucose uptake with an IC50 of 2.6 μM, and effectively suppresses parasite growth with an EC50 of 1.23±0.04 μM against the 3D7 strain. Its dual action on both the malaria parasite and human glucose transporters positions it as a valuable tool for research in malaria treatment and metabolism studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 298217-59-1 |
| Applications | PfHT1 Inhibitor |
| Formula | C22H22N2O6 |
| Molecular Weight | 410.42 |
| SMILES | O=C1C2=CC=C3C(N(CCCCO)C(C4=CC=C(C2=C34)C(N1CCCCO)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.