Fig. 1 · Structure

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MMV019313

FPPS/GGPPS Inhibitor

MMV019313 is a potent non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS), exhibiting an IC50 value of 0.82 µM. This compound demonstrates significant biological activity against Plasmodium falciparum, making it a valuable tool for research in antimalarial drug development. MMV019313 may be utilized in studies focused on the biochemical pathways of parasitic infections and the synthesis of isoprenoids.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 902630-14-2
Applications FPPS/GGPPS Inhibitor
Formula C22H27N3O2S
Molecular Weight 397.53
SMILES
O=C(C(S1)=CC2=C1C3=C(N(C)C2=O)C=CC=C3)NCCCN4CCCCCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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