Fig. 1 · Structure

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MMV019662

PfNCR1 Inhibitor

MMV019662 is a selective inhibitor of PfNCR1, a critical enzyme in the life cycle of Plasmodium falciparum. By specifically interacting with PfNCR1, MMV019662 induces the opening of the substrate-binding site domain (SSD), disrupting the function of this target. This compound serves as a valuable tool in researching the mechanisms of Plasmodium falciparum infection and developing potential therapeutic strategies against malaria.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 896349-19-2
Applications PfNCR1 Inhibitor
Formula C27H35N3O4
Molecular Weight 465.59
SMILES
O=C(NCC(C1=CC=C2OCOC2=C1)N3CCN(C4=CC=C(OC)C=C4)CC3)C5CCCCC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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