Fig. 1 · Structure

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MMV665917

Anti-Cryptosporidium parvum Agent

MMV665917 is an orally active piperazine derivative that targets Cryptosporidium parvum, exhibiting an effective concentration (EC90) of 15 μM. This compound significantly lowers parasite loads in porcine models infected with C. hominis, while also reducing ovarian excretion and alleviating diarrhea symptoms, leading to decreased intestinal mucosal damage. MMV665917 serves as a valuable tool for researchers investigating Cryptosporidium parvum infections and associated disease mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 904576-65-4
Applications Anti-Cryptosporidium parvum Agent
Formula C16H16ClN7O
Molecular Weight 357.80
SMILES
O=C(NC1=CC=C(C([H])=C1)Cl)N2CCN(CC2)C3=NN4C(C=C3)=NN=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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