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MN551

Cysteine-directed Electrophilic Covalent Inhibitor

MN551 is a potent cysteine-directed electrophilic covalent inhibitor that targets proteins involved in the biological functions of SOCS2 and its CRL5 complex. This compound serves as a valuable tool in research focused on E3 ligase mediated processes, including proteolysis targeting chimera (PROTAC) strategies, to facilitate targeted protein degradation. Its unique mechanism offers insights into the regulation of protein homeostasis and potential therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3044099-90-0
Applications	Cysteine-directed Electrophilic Covalent Inhibitor
Formula	C₂₆H₂₆ClFN₃O₇P
Molecular Weight	577.93
SMILES	FC1=CC=C(CC(N[C@@H](CC2=CC=C(OP(O)(O)=O)C=C2)C(NCC3=CC=CC(NC(CCl)=O)=C3)=O)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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MN551

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MN551 1 mg