Fig. 1 · Structure

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MNI-caged-NMDA

iGluR

MNI-caged-NMDA is a light-sensitive compound designed to target ionotropic glutamate receptors (iGluRs) through photolytic release. This reagent exhibits fast and controlled activation of NMDA receptors, allowing for the study of synaptic mechanisms in cerebellar interneurons. By employing local laser photolysis, MNI-caged-NMDA facilitates rapid transient responses and generates significant inward currents. This compound is ideal for investigating neurotransmitter signaling dynamics and exploring the effects on GABA-A receptor function.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1227675-52-6
Applications iGluR
Formula C14H17N3O6
Molecular Weight 323.30
SMILES
O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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