Fig. 1 · Structure
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MNK inhibitor 9
MNK1/2 Inhibitor
MNK inhibitor 9 is a potent and selective inhibitor of MNK1 and MNK2, exhibiting IC50 values of 0.003 µM for both isoforms. This compound demonstrates excellent cell permeability, making it suitable for in vitro studies. MNK inhibitor 9 is particularly relevant for research focusing on tumor biology and related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1889336-59-7 |
| Applications | MNK1/2 Inhibitor |
| Formula | C25H29N9O |
| Molecular Weight | 471.56 |
| SMILES | O=C(C1=CC(C2=NC(C3=NC4=CC=CC(N5C[C@H](C)NCC5)=C4N3C)=C(N)N=C2)=NC=C1)N(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.