Fig. 1 · Structure

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MNK1/2-IN-5

MNK1/2 Inhibitor

MNK1/2-IN-5 is a highly selective inhibitor of MNK1 and MNK2, targeting these kinases to modulate their downstream signaling pathways. This compound demonstrates significant biological activity by disrupting cap-dependent translation, which may impact oncogenic processes. Its utility in research includes exploring mechanisms of cancer biology and evaluating potential therapeutic strategies for targeting MNK-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1426928-20-2
Applications MNK1/2 Inhibitor
Formula C17H16N4O2
Molecular Weight 308.33
SMILES
NC[C@@H](C)OC1=NN2C(C3=CC4=CC=CC=C4O3)=CN=C2C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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