Documents & Downloads

MNK1/2-IN-6

MNK1/2 Inhibitor

MNK1/2-IN-6 is a selective inhibitor of MNK1 and MNK2, exhibiting IC50 values of 2.3 nM for MNK1 and 3.4 nM for MNK2. This compound effectively induces apoptosis in a concentration-dependent manner, making it a valuable tool for studying the role of MNK kinases in cellular processes. Its application in cancer research and other therapeutic areas highlights its potential in elucidating the molecular mechanisms underlying MNK-mediated signaling pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2771087-94-4
Applications	MNK1/2 Inhibitor
Formula	C₂₇H₂₄N₆O
Molecular Weight	448.52
SMILES	N[C@H]1CCCN(C1)C(C2=CC=C(C=C2)C3=NN4C(C5=CC=C6C=NC=CC6=C5)=CN=C4C=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.