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MNK1/2-IN-8

MNK1/2 Inhibitor

MNK1/2-IN-8 is a potent inhibitor of MNK1 and MNK2, exhibiting IC50 values of 0.8 nM and 1.5 nM, respectively. This compound demonstrates significant anti-proliferative activity and effectively induces cell cycle arrest in cancer cells. MNK1/2-IN-8 is suitable for research applications focused on understanding the role of MNK signaling in cellular proliferation and apoptosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2430793-35-2
Applications	MNK1/2 Inhibitor
Formula	C₂₆H₂₄N₆O
Molecular Weight	436.51
SMILES	O=C(N1CCNCC1)C2=CC=CC(C3=NC4=C(N=CN=C4N5CCC6=C5C=CC=C6)C=C3)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.