Fig. 1 · Structure

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Modimelanotide

a-melanocyte Stimulating Hormone Analog

Modimelanotide is an α-melanocyte-stimulating hormone analog that exhibits high specificity for melanocortin receptors MCR1, MCR3, MCR4, and MCR5. This compound demonstrates notable anti-inflammatory and organ-protective properties, making it a valuable tool for research in conditions such as acute kidney injury. Investigating Modimelanotide can enhance understanding of melanocortin receptor signaling and its implications in various disease contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 926277-68-1
Applications a-melanocyte Stimulating Hormone Analog
Formula C113H181N33O25S
Molecular Weight 2433.92
Synonyms ABT-719; AP-214
SMILES
C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC(C)=O)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CO)=O)=O)CO)=O)CCSC)=O)CCC(O)=O)=O)=O)=O)CCCNC(=N)N)=O)C(NCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C(C)C)C(N)=O)=O)CCC4)CCCCN)=O)=O)C=5C=6C(NC5)=CC=CC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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