Fig. 1 · Structure

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MOG (35-55) mouse, rat

CNS Myelin Component

MOG (35-55) is a peptide derived from the Myelin Oligodendrocyte Glycoprotein that targets central nervous system (CNS) myelin components. This peptide exhibits encephalitogenic properties, effectively inducing T cell proliferation and promoting a Th1 cytokine response, along with elevated levels of IgG antibodies. MOG (35-55) is instrumental in modeling experimental autoimmune encephalomyelitis (EAE), a condition characterized by relapsing-remitting neurological disease and significant plaque-like demyelination. Its application is critical for understanding demyelinating disorders in research settings.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 149635-73-4
Applications CNS Myelin Component
Formula C118H177N35O29S
Molecular Weight 2581.95
Synonyms Myelin Oligodendrocyte Glycoprotein Peptide (35-55); mouse; rat
SMILES
CSCCC(N)C(=O)NC(CCC(O)=O)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NCC(=O)NC(CCCCN)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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