Fig. 1 · Structure
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Moiramide B
ACC Inhibitor
Moiramide B is a selective inhibitor of acetyl-CoA carboxylase (ACC) with an IC50 of 6 nM, demonstrating potent enzymatic inhibition. This compound exhibits antibacterial activity, thereby providing a valuable tool for research in metabolic regulation and microbiology. Its application extends to studies exploring ACC's role in lipid metabolism and potential therapeutic approaches against bacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 155233-31-1 |
| Applications | ACC Inhibitor |
| Formula | C25H31N3O5 |
| Molecular Weight | 453.53 |
| SMILES | O=C(N1)[C@@H](C([C@H](C(C)C)NC(C[C@H](NC(/C=C/C=C/C)=O)C2=CC=CC=C2)=O)=O)[C@H](C)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.