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Form	MW
Molidustat sodium This page	336.28
Molidustat	314.3

Molidustat sodium

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

Molidustat sodium is a potent inhibitor of hypoxia-inducible factor prolyl hydroxylases (HIF-PHs), exhibiting IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3. By inhibiting these enzymes, Molidustat sodium effectively increases circulating erythropoietin (EPO) levels, contributing to the regulation of erythropoiesis. This reagent is particularly valuable for research focused on renal anemia and the physiological responses to hypoxia.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1375799-59-9
Applications	Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor
Formula	C₁₃H₁₃N₈NaO₂
Molecular Weight	336.28
SMILES	[Na]OC1=C(N2N=NC=C2)C=NN1C3=NC=NC(N4CCOCC4)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.