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Monalizumab
Monalizumab (IPH2201) is a humanized monoclonal antibody designed to inhibit the immune checkpoint receptor Natural Killer Group 2A (NKG2A). By blocking NKG2A, Monalizumab enhances interferon-gamma (IFN-γ) production, which in turn augments the effector functions of natural killer (NK) cells. This antibody is primarily utilized in research focused on understanding and treating head and neck squamous cell carcinoma (HNSCC).
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1228763-95-8 |
| Molecular Weight | 145000 |
| Synonyms | IPH2201 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.