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Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.2 mL | 171 mL | 342 mL |
| 0.5 mM | 6.84 mL | 34.2 mL | 68.4 mL |
| 1 mM | 3.42 mL | 17.1 mL | 34.2 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
*The above data is based on the productmolecular weight 292.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11976 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 292.4 |
| Formula | C14H16N2O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 329689-23-8 |
| Synonyms | N/A |
| SMILES | CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C |
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