Monastrol

Catalog No.: A11976

Kinesin-5(KIF11) inhibitor

Monastrol

Monastrol Chemical Structure

CAS NO. 329689-23-8

Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$110.00
25 mg
$230.00
50 mg
$390.00
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Biological Activity

Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.
In vitro DMSO 54 mg/mL (184.71 mM)
Water Insoluble
Ethanol 54 mg/mL (184.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.2 mL 171 mL 342 mL
0.5 mM 6.84 mL 34.2 mL 68.4 mL
1 mM 3.42 mL 17.1 mL 34.2 mL
5 mM 0.68 mL 3.42 mL 6.84 mL

*The above data is based on the productmolecular weight 292.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11976
Actions Inhibitor
CAS No. 329689-23-8
Formula C14H16N2O3S
M. Wt 292.4
Purity >98%
SMILES CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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