Fig. 1 · Structure
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Mono N-desmethyl disperse polyester dark blue
Bioreductive agent
Mono N-Desmethyl Disperse Polyester Dark Blue is a bioreductive agent that is activated in hypoxic environments. Upon entering a cell, it undergoes reduction to its active form, resulting in the generation of reactive oxygen species that can induce cellular damage, particularly affecting DNA. This compound is particularly effective in targeting hypoxic cancer cells, which are already under stress, and has been shown to inhibit hypoxia-inducible factor 1 (HIF-1), a crucial regulator of the cellular response to low oxygen levels. Its unique mechanism makes it a valuable tool in cancer research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 56524-77-7 |
| Applications | Bioreductive agent |
| Formula | C15H12N2O4 |
| Molecular Weight | 284.27 |
| SMILES | O=C1C2=C(C(C3=C1C(O)=CC=C3NC)=O)C(N)=CC=C2O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.