Fig. 1 · Structure
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Monoethyl phthalate
PDX-1 Activator
Monoethyl phthalate is an orally active PDX-1 activator with implications in reproductive toxicity research. As the primary hydrolytic metabolite of diethyl phthalate, it targets aromatase (CYP19A1) and peroxisome proliferator-activated receptors (PPAR) to promote cell proliferation. Notably, monoethyl phthalate demonstrates significant enterohepatic circulation and is predominantly accumulated in liver tissues, without exhibiting estrogenic activity in estrogen-dependent human breast cancer cells. This compound serves as a valuable tool in studies addressing reproductive toxicity and environmental endocrine disruption mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2306-33-4 |
| Applications | PDX-1 Activator |
| Formula | C10H10O4 |
| Molecular Weight | 194.19 |
| SMILES | O=C(C1=CC=CC=C1C(O)=O)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.