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Monophosphoryl Lipid A-12

Catalog No.: A35373
TLR4 Agonist
Monophosphoryl Lipid A-12 (MPLA-12) is a potent agonist of Toll-like receptor 4 (TLR4). It exhibits important biological activity in modulating immune responses, making it a valuable tool for immunization studies and vaccine research. Its ability to stimulate TLR4 signaling cascades positions MPLA-12 as a key compound for investigating immune system activation and potential therapeutic applications in infectious diseases and cancer vaccines.
Monophosphoryl Lipid A-12 1332714-01-8 TLR4 Agonist
Grouped product items
Size Price Stock Qty
1mg
$590.00
In stock
5mg
$1,975.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMonophosphoryl Lipid A-12 (MPLA-12) is a potent agonist of Toll-like receptor 4 (TLR4). It exhibits important biological activity in modulating immune responses, making it a valuable tool for immunization studies and vaccine research. Its ability to stimulate TLR4 signaling cascades positions MPLA-12 as a key compound for investigating immune system activation and potential therapeutic applications in infectious diseases and cancer vaccines.
Product Information
Catalog NumA35373
FormulaC94H180N3O22P
Molecular Weight1735.42
CAS Number1332714-01-8
SMILESCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(C[C@H](O)CCCCCCCCCCC)=O)OC(C[C@H](O)CCCCCCCCCCC)=O)O)CO)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O)=O)=O.N
SynonymsMPLA-12
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Immunology & Inflammation > Toll-like Receptors