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Monophosphoryl lipid A free acid

Catalog No.: A35495
TLR Agonist
Monophosphoryl lipid A free acid acts as a toll-like receptor 4 (TLR4) agonist, stimulating innate immune responses. Derived from the cell wall of nonpathogenic Salmonella, this compound is relevant for research into immunization and vaccine development. Its ability to activate TLR4 makes it a valuable tool for studying immune modulation and potentially enhancing vaccine efficacy.
Monophosphoryl lipid A free acid 960324-04-3 TLR Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMonophosphoryl lipid A free acid acts as a toll-like receptor 4 (TLR4) agonist, stimulating innate immune responses. Derived from the cell wall of nonpathogenic Salmonella, this compound is relevant for research into immunization and vaccine development. Its ability to activate TLR4 makes it a valuable tool for studying immune modulation and potentially enhancing vaccine efficacy.
Product Information
Catalog NumA35495
FormulaC96H181N2O22P
Molecular Weight1746.44
CAS Number960324-04-3
SMILESCCCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(C[C@H](O)CCCCCCCCCCC)=O)OC(C[C@H](O)CCCCCCCCCCC)=O)O)CO)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O)=O)=O
SynonymsGlucopyranosyl lipid A free acid
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Immunology & Inflammation > Toll-like Receptors