Fig. 1 · Structure

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Monophosphoryl lipid A

Toll-Like Receptor 4 Agonist

Monophosphoryl lipid A is a potent agonist of Toll-Like Receptor 4 (TLR4), playing a critical role in immune system activation. Derived from the cell wall of nonpathogenic Salmonella, this compound is instrumental in research focused on immunization and vaccine development. Monophosphoryl lipid A enhances the immune response and is valuable for studies investigating adjuvants and immune modulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 1246298-63-4
Applications Toll-Like Receptor 4 Agonist
Formula C96H184N3O22P
Molecular Weight 1763.47
Synonyms Glucopyranosyl lipid A
SMILES
CCCCCCCCCCCCCC(O[C@@H](CC(N[C@@H]1[C@@H](OC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)[C@H](OP(O)([O-])=O)[C@@H](CO)O[C@H]1OC[C@@H]2[C@@H](O)[C@H](OC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H](NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H](O)O2)=O)CCCCCCCCCCC)=O.[NH4+]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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