Fig. 1 · Structure
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Moricizine-d8 Hydrochloride
Stable Isotope
Moricizine-d8 Hydrochloride is a deuterated form of Moricizine Hydrochloride, serving as a stable isotope labeled analogue. This compound acts as a Class I antiarrhythmic agent, modulating cardiac action potentials by decreasing the maximum rate of phase 0 depolarization, increasing rates of phase 2 and 3 repolarization, and ultimately reducing action potential duration and effective refractory period. It is useful in pharmacokinetic studies and metabolic research, providing insights into the pharmacodynamics of antiarrhythmic therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2300178-76-9 |
| Applications | Stable Isotope |
| Formula | C22H18D8ClN3O4S |
| Molecular Weight | 472.03 |
| Synonyms | EN 313-d8; Ethmozin-d8; Moracizine-d8 |
| SMILES | [2H]C1([2H])C([2H])([2H])OC([2H])([2H])C([2H])([2H])N1CCC(N2C3=CC(NC(OCC)=O)=CC=C3SC4=CC=CC=C42)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.