Fig. 1 · Structure
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Mosapride citrate dihydrate
5HT4 Agonist
Mosapride citrate dihydrate is a 5-HT4 receptor agonist that serves as a gastroprokinetic agent. It enhances gastrointestinal motility by selectively stimulating upper gastrointestinal function. Additionally, Mosapride demonstrates a concentration-dependent inhibition of Kv4.3 channels, with an IC50 value of 15.2 μM, making it valuable in research related to various gastrointestinal disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 636582-62-2 |
| Applications | 5HT4 Agonist |
| Formula | C27H37ClFN3O12 |
| Molecular Weight | 650.05 |
| Synonyms | TAK-370 citrate dihydrate; AS-4370 citrate dihydrate |
| SMILES | O=C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)C3=CC(Cl)=C(N)C=C3OCC.O=C(CC(C(O)=O)(O)CC(O)=O)O.O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.