Fig. 1 · Structure
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Motexafin gadolinium
Antitumor Agent
Motexafin gadolinium is a potent antitumor agent that functions by increasing intracellular reactive oxygen species (ROS) production. As a specific texaphyrin complexed with gadolinium(III), it enhances the sensitivity of tumor cells to ionizing radiation, making it valuable for cancer research. This compound is particularly useful in investigating radiotherapy and its interaction with oxidative stress pathways in tumor biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 246252-06-2 |
| Applications | Antitumor Agent |
| Formula | C52H72GdN5O14 |
| Molecular Weight | 1148.40 |
| Synonyms | PCI 0120; Gadolinium texaphyrin; Gd-Tex |
| SMILES | CC([O-][Gd+3]1234([N-]5C6=C(CC)C(CC)=C5C=C7[N]1=C(C(C)=C7CCCO)C=[N]2C8=CC(OCCOCCOCCOC)=C(OCCOCCOCCOC)C=C8[N]3=CC(C(C)=C9CCCO)=[N]4C9=C6)[O-]C(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.