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- Hiroshi Arakawa, .et al. Possible interaction of quinolone antibiotics with peptide transporter 1 in oral absorption of peptide-mimetic drugs, Biopharm Drug Dispos, 2016, Jan;37(1):39-45 PMID: 26590007
- Arisa Higa, .et al. Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements, Fundam. Toxicol. Sci, 2016, 3(2): 47-53
Biological Activity
Moxifloxacin is a quinolone/fluoroquinolone antibiotic.
Targets
| Topoisomerase II | Topoisomerase IV | |||
| In vitro (25°C) | DMSO | 77 mg/mL (175.84 mM) | |
| Water | 53 mg/mL (121.03 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.84 mL | 114.18 mL | 228.36 mL |
| 0.5 mM | 4.57 mL | 22.84 mL | 45.67 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10609 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 186826-86-8 |
| Formula | C21H24FN3O4.HCl |
| M. Wt | 437.9 |
| Purity | >98% |
| Synonyms | Avelox, Avalox, BAY 12-8039 |
| SMILES | COC1=C2C(=CC(=C1N3C[[email protected]@H]4CCCN[[email protected]@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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