Moxonidine-d4

Catalog No.: A58747
Stable Isotope
Moxonidine-d4 is a deuterium-labeled analogue of Moxonidine, which functions primarily as an imidazoline type 1 receptor (I1-R) agonist. This compound activates I1 receptors and α2 adrenoceptors, modulating the uptake of oxidized low-density lipoprotein. Moxonidine has been shown to effectively reduce atherosclerotic lesions and lower blood pressure, making it a valuable tool for researching hypertension, heart failure, and atherosclerosis.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMoxonidine-d4 is a deuterium-labeled analogue of Moxonidine, which functions primarily as an imidazoline type 1 receptor (I1-R) agonist. This compound activates I1 receptors and α2 adrenoceptors, modulating the uptake of oxidized low-density lipoprotein. Moxonidine has been shown to effectively reduce atherosclerotic lesions and lower blood pressure, making it a valuable tool for researching hypertension, heart failure, and atherosclerosis.
Product Information
Catalog NumA58747
FormulaC9H8D4ClN5O
Molecular Weight245.70
CAS Number1794811-52-1
SMILESN(C=1C(OC)=NC(C)=NC1Cl)C=2NC(C(N2)([2H])[2H])([2H])[2H]
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