Fig. 1 · Structure
Documents & Downloads
Mozavaptan hydrochloride
Vasopressin V2 Receptor Antagonist
Mozavaptan hydrochloride is a potent and selective antagonist of the vasopressin V2 receptor, exhibiting an IC50 of 14 nM. This benzazepine derivative demonstrates approximately 85-fold selectivity for the V2 receptor compared to the V1 receptor (IC50 of 1.2 μM) and effectively antagonizes the antidiuretic effects of arginine vasopressin (AVP) in vivo. It holds potential for research applications in treating conditions such as hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 138470-70-9 |
| Applications | Vasopressin V2 Receptor Antagonist |
| Formula | C27H30ClN3O2 |
| Molecular Weight | 464.00 |
| Synonyms | OPC-31260 hydrochloride |
| SMILES | CC1=CC=CC=C1C(NC2=CC=C(C(N3C(C=CC=C4)=C4C(N(C)C)CCC3)=O)C=C2)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.