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MPPG

mGluR Antagonist

MPPG is a selective antagonist of metabotropic glutamate receptors (mGluRs), specifically targeting L-AP4-sensitive receptors with a KD value of 9.2 μM. This reagent demonstrates significant inhibition of mGluR activity, making it valuable for studying excitatory neurotransmission and synaptic plasticity. Its applications include investigating the role of mGluRs in various neurological conditions using neonatal rat spinal cord models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	169209-65-8
Applications	mGluR Antagonist
Formula	C₉H₁₂NO₅P
Molecular Weight	245.17
SMILES	O=C(O)C(C)(N)C1=CC=C(P(O)(O)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.