MPPG is a selective antagonist of metabotropic glutamate receptors (mGluRs), specifically targeting L-AP4-sensitive receptors with a KD value of 9.2 μM. This reagent demonstrates significant inhibition of mGluR activity, making it valuable for studying excitatory neurotransmission and synaptic plasticity. Its applications include investigating the role of mGluRs in various neurological conditions using neonatal rat spinal cord models.
MPPG is a selective antagonist of metabotropic glutamate receptors (mGluRs), specifically targeting L-AP4-sensitive receptors with a KD value of 9.2 μM. This reagent demonstrates significant inhibition of mGluR activity, making it valuable for studying excitatory neurotransmission and synaptic plasticity. Its applications include investigating the role of mGluRs in various neurological conditions using neonatal rat spinal cord models.
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