Fig. 1 · Structure
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Mps-BAY1
MPS1 Inhibitor
Mps-BAY1 is an inhibitor of MPS1, a critical kinase involved in the regulation of cell cycle and mitosis. This compound demonstrates significant anticancer activity by inhibiting cell proliferation and inducing apoptosis through the activation of mitotic catastrophe, leading to global aneuploidy and polyploidy in cancer cells. Mps-BAY1 is applicable in research related to colorectal cancer and cervical cancer, making it a valuable tool for studying mechanisms underlying tumorigenesis and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1309593-24-5 |
| Applications | MPS1 Inhibitor |
| Formula | C27H20N6O |
| Molecular Weight | 444.49 |
| SMILES | N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.