Fig. 1 · Structure
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Mps-BAY2a
MPS1 Inhibitor
Mps-BAY2a is a potent inhibitor of monopolar spindle 1 (MPS1) with an IC50 of 1 nM in human MPS1. This compound effectively induces mitotic aberrations and promotes apoptosis in cancer cells, making it a valuable tool for cancer research and studies focused on cell cycle regulation. Its high specificity for MPS1 underscores its potential in investigating the role of this kinase in mitotic progression and tumorigenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1382477-96-4 |
| Applications | MPS1 Inhibitor |
| Formula | C29H28N6O |
| Molecular Weight | 476.57 |
| SMILES | O=C(C1=CC=C(C2=CN=C3C(NCC(C)C)=NC(C4=C5C=CC=NC5=CC=C4)=CN32)C=C1)NC6CC6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.