Mps1-IN-10 is a potent inhibitor of Mps1, exhibiting an IC50 of 6.4 nM. This compound effectively suppresses the proliferation of cancer cells, demonstrated by a GI50 of 11 nM in the MDA-MB-231 cell line. Mps1-IN-10 also shows significant anti-tumor efficacy in preclinical models using MDA-MB-231 xenografts, making it a valuable tool for cancer research applications focused on cell cycle regulation and tumor growth inhibition.
Mps1-IN-10 is a potent inhibitor of Mps1, exhibiting an IC50 of 6.4 nM. This compound effectively suppresses the proliferation of cancer cells, demonstrated by a GI50 of 11 nM in the MDA-MB-231 cell line. Mps1-IN-10 also shows significant anti-tumor efficacy in preclinical models using MDA-MB-231 xenografts, making it a valuable tool for cancer research applications focused on cell cycle regulation and tumor growth inhibition.
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