Fig. 1 · Structure
Documents & Downloads
Mps1-IN-3 hydrochloride
Cat. No.
A55065
CAS
2989453-29-2
Mps1 Inhibitor
Mps1-IN-3 hydrochloride is a potent and selective inhibitor of Mps1, with an IC50 value of 50 nM. This compound effectively inhibits the proliferation of glioblastoma cells and enhances the sensitivity of glioblastomas to Vincristine in orthotopic glioblastoma xenograft models. Mps1-IN-3 hydrochloride is valuable for research applications targeting cell cycle regulation and glioblastoma treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2989453-29-2 |
| Applications | Mps1 Inhibitor |
| Formula | C26H32ClN7O4S |
| Molecular Weight | 574.09 |
| SMILES | OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.