Fig. 1 · Structure
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Mps1-IN-5
Mps1 Inhibitor
Mps1-IN-5 is a selective inhibitor of Mps1 kinase, exhibiting an IC50 value of 29 nM. This compound effectively induces apoptosis and triggers cell cycle arrest at the G2/M phase, demonstrating significant antiproliferative and anti-tumor activities. Mps1-IN-5 operates by inhibiting Mps1 phosphorylation and promoting DNA damage, making it a valuable tool for cancer research and therapeutic investigations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2890819-31-3 |
| Applications | Mps1 Inhibitor |
| Formula | C24H25N9 |
| Molecular Weight | 439.52 |
| SMILES | CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(N5N=C(C6=CC=CC=C65)N)=N3)C=CN4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.