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Fig. 1 · Structure
Cat. No.
A30087
CAS No.
28289-54-5
Formula
C12H15N
Mol. Weight
173.25

Documents & Downloads

MPTP

Dopaminergic Neurotoxin

MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a potent dopaminergic neurotoxin that readily penetrates the blood-brain barrier. It is primarily utilized to create animal models of Parkinson’s Disease, enabling the study of neurodegenerative processes. MPTP acts by converting into MPP+, which induces apoptosis in dopaminergic neurons, serving as a valuable tool for investigating therapeutic strategies and the underlying mechanisms of neurodegeneration.

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Publications for MPTP

2 publications citing this product

  1. Sai Teja Meka, .et al. , Eur J Pharmacol, 2023, Nov 15:959:176067 PMID: 37751833
  2. Philemon Dauda Shallie, .et al. , Annual Research & Review in Biology, 2017, 13(5): 1-11
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For laboratory research use only. We do not sell to patients.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 28289-54-5
Applications Dopaminergic Neurotoxin
Formula C12H15N
Molecular Weight 173.25
SMILES
CN1CC=C(CC1)C2=CC=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Publications

2 publications citing this product

  1. Sai Teja Meka, .et al. , Eur J Pharmacol, 2023, Nov 15:959:176067 PMID: 37751833
  2. Philemon Dauda Shallie, .et al. , Annual Research & Review in Biology, 2017, 13(5): 1-11

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