Fig. 1 · Structure
Documents & Downloads
MPX-004
GluN2A Antagonist
MPX-004 is a selective antagonist of the GluN2A subunit of NMDA receptors. It exhibits potent inhibition with an IC50 of 79 nM in HEK cells, demonstrating specificity as it does not affect GluN2B or GluN2D receptor-mediated responses. This compound holds promise for research into neuropsychiatric and developmental disorders, providing a valuable tool for investigating the role of GluN2A in various neurological conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1688684-07-2 |
| Applications | GluN2A Antagonist |
| Formula | C17H15ClFN5O3S2 |
| Molecular Weight | 455.91 |
| SMILES | O=C(C1=NC=C(CNS(=O)(C2=CC=C(C(Cl)=C2)F)=O)N=C1)NCC3=CN=C(C)S3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.