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MPXV p37 protein-IN-1

MPXV p37 Protein Inhibitor

MPXV p37 protein-IN-1 is a potent inhibitor targeting the monkeypox virus (MPXV) p37 protein. It displays significant antiviral activity, with an EC50 of 12.14 nM, and exhibits low cytotoxicity, evidenced by a CC50 of 304.63 μM. With demonstrated tolerability and low toxicity in murine models, this compound is valuable for research focused on developing therapeutic strategies against MPXV infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3096845-40-5
Applications	MPXV p37 Protein Inhibitor
Formula	C₁₈H₁₅F₂N₃O₂S
Molecular Weight	375.39
SMILES	[H][C@@]12[C@@]3([H])C[C@@]3([H])[C@@]([C@](C(N4NC(NC5=CC(F)=C(F)C=C5)=S)=O)([H])[C@@]2([H])C4=O)([H])C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.