Documents & Downloads

MRC71

TRIMTAC Halo Degrader

MRC71 is a TRIMTAC degrader designed to target the Halo Tag, utilizing a PEG linker and chloroalkane moiety for enhanced specificity. This compound selectively induces the degradation of oligomeric CAV1- and Cavin1-mEGFP-Halo constructs while sparing monomeric mEGFP-Halo. MRC71 displays a characteristic hook effect, demonstrating concentration-dependent degradation profiles, making it a valuable tool for studying protein regulation and turnover in cellular models.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3070832-68-4
Applications	TRIMTAC Halo Degrader
Formula	C₄₃H₆₆ClN₅O₈
Molecular Weight	816.47
SMILES	O=C(C[C@H](N)C1=C(OC)C=CC=C1)N(C2)[C@H](C(N[C@@H](CC3=CC=NC=C3)C(NCCOCCOCCOCCOCCCCCCCl)=O)=O)C[C@H]2C4CCCCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.