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MrgprX2 antagonist-11

MrgprX2 Antagonist

MrgprX2 antagonist-11 is a selective antagonist for the Mas-related G protein-coupled receptor X2 (MrgprX2), exhibiting an IC50 of less than 100 nM. This compound plays a significant role in the investigation of inflammatory diseases by modulating pathways associated with pain and immune response. Research applications include studying the physiological and pathological functions of MrgprX2 in various inflammatory conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	3116847-13-0
Applications	MrgprX2 Antagonist
Formula	C₂₆H₂₈FN₅O₄
Molecular Weight	493.53
SMILES	O=C(C(C=C1)=CNC1=O)N2C(C)(CN(CC2)[C@@H](C)C(NC3=CC=C(C=N3)OC4=CC=C(C=C4)F)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.