MRS2179 tetrasodium is a competitive antagonist of the P2Y1 receptor, demonstrating a Kb value of 102 nM and a pA2 of 6.99 for the turkey P2Y1 receptor. This compound exhibits selectivity for P2Y1 over other purinergic receptors, including P2X1 (IC50 = 1.15 µM) and P2X3 (IC50 = 12.9 µM). MRS2179 tetrasodium is particularly useful in studies of platelet aggregation and various signaling pathways involving purinergic receptors.
MRS2179 tetrasodium is a competitive antagonist of the P2Y1 receptor, demonstrating a Kb value of 102 nM and a pA2 of 6.99 for the turkey P2Y1 receptor. This compound exhibits selectivity for P2Y1 over other purinergic receptors, including P2X1 (IC50 = 1.15 µM) and P2X3 (IC50 = 12.9 µM). MRS2179 tetrasodium is particularly useful in studies of platelet aggregation and various signaling pathways involving purinergic receptors.
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