Biological Activity
MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.57 mL | 92.83 mL | 185.67 mL |
0.5 mM | 3.71 mL | 18.57 mL | 37.13 mL |
1 mM | 1.86 mL | 9.28 mL | 18.57 mL |
5 mM | 0.37 mL | 1.86 mL | 3.71 mL |
*The above data is based on the productmolecular weight 538.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21020 |
---|---|
Actions | Antagonist |
M. Wt | 538.59 |
Formula | C31H30N4O5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1263131-92-5 |
Synonyms | MRT83, MRT 83 |
SMILES | COC1=C(OC)C(OC)=CC(C(NC(NC2=CC(NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=C(C)C=C2)=N)=O)=C1 |
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