MRTX0902

Name: MRTX0902
Brand: Adooq Bioscience
SKU: A24525
Rating: 5 (288 reviews)

Catalog No.: A24525

SOS1 inhibitor

MRTX0902 is an orally active and potent SOS1 inhibitor, exhibiting an IC₅₀ of 46 nM (WO2021127429A1; Example 12-10). It is designed to disrupt the SOS1–KRAS interaction, making it a promising candidate for targeting KRAS-driven cancers.

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Grouped product items
Size	Price	Stock
5mg	$198.00	In stock
10mg	$341.00	In stock
50mg	$1,012.00	In stock
100mg	$1,980.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	MRTX0902 is an orally active and potent SOS1 inhibitor, exhibiting an IC₅₀ of 46 nM (WO2021127429A1; Example 12-10). It is designed to disrupt the SOS1–KRAS interaction, making it a promising candidate for targeting KRAS-driven cancers.

Product Information

Catalog Num	A24525
Formula	C22H24N6O
Molecular Weight	388.47
CAS Number	2654743-22-1
SMILES	C[C@H](C1=C(C(C#N)=CC=C1)C)NC2=NN=C(C)C3=C2C=C(N4CCOCC4)N=C3
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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