Catalog No.: A16958

MERTK and FLT3 inhibitor


MRX-2843 Chemical Structure

CAS NO. 1429882-07-4

MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.

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Biological Activity

MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.
In vitro DMSO 97 mg/mL (198.49 mM)
Water Insoluble
Ethanol 25 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.46 mL 102.32 mL 204.64 mL
0.5 mM 4.09 mL 20.46 mL 40.93 mL
1 mM 2.05 mL 10.23 mL 20.46 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16958
Actions Inhibitor
CAS No. 1429882-07-4
Formula C29H40N6O
M. Wt 488.67
Purity >98%
Synonyms MRX2843, MRX 2843, UNC-2371, UNC 2371, UNC2371
SMILES O[[email protected]]1CC[[email protected]](N2C=C(C3=CC=C(CN4CCN(C)CC4)C=C3)C5=CN=C(NCCC6CC6)N=C52)CC1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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