Fig. 1 · Structure
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MS-0022
SMO Antagonist
MS-0022 is a Smoothened (SMO) antagonist that effectively inhibits the Hedgehog (Hh) signaling pathway. Through its modulation of this pathway, MS-0022 demonstrates potential in anti-tumor research by suppressing tumor growth and proliferation linked to aberrant Hh signaling. This compound is suitable for studies investigating the role of the Hedgehog pathway in cancer and other related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 691392-89-9 |
| Applications | SMO Antagonist |
| Formula | C21H16BrN3O |
| Molecular Weight | 406.28 |
| SMILES | O=C(NC1=CC=C(C2=CN3C=CC=C(C)C3=N2)C=C1)C4=CC=CC=C4Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.