Fig. 1 · Structure

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MS1262

E3 ubiquitin ligase ligand

MS1262 is a selective ligand for the E3 ubiquitin ligase SPOP, targeting the SPOP substrate GLP. This compound facilitates the recruitment of SPOP and is utilized in research to study ubiquitination processes and related signaling pathways. MS1262 serves as a precursor for the synthesis of MS479, further expanding its utility in chemical biology investigations.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3070323-06-4
Applications E3 ubiquitin ligase ligand
Formula C29H45N5O3
Molecular Weight 511.70
SMILES
COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(N4CCOCC4)C=C2NC5CCN(C(C)C)CC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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