Fig. 1 · Structure
Documents & Downloads
MS154N
MS39 Negative Control
MS154N is a negative control for the selective degradation of target proteins via the PROTAC (proteolysis targeting chimera) approach. Comprising an EGFR ligand, an E3 ligase ligand, and a PROTAC linker, this compound serves as a crucial investigational tool for validating the specificity and efficacy of PROTAC-based assays. Its design facilitates research into targeted protein degradation mechanisms, providing a reliable reference for experimental protocols involving MS39.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2675490-97-6 |
| Applications | MS39 Negative Control |
| Formula | C47H56ClFN8O8 |
| Molecular Weight | 915.45 |
| SMILES | O=C1C2=C(C(N1C3C(N(C)C(CC3)=O)=O)=O)C(OCCCCCCCCNC(CCN4CCN(CCCOC5=CC6=C(NC7=CC=C(C(Cl)=C7)F)N=CN=C6C=C5OC)CC4)=O)=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.