Fig. 1 · Structure

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MS159

PROTAC NSD2 Degrader

MS159 is a potent PROTAC degrader targeting nuclear receptor binding SET domain protein 2 (NSD2). It effectively inhibits tumor cell growth, making it a valuable tool for investigating the biological functions of NSD2 in various health and disease contexts. This compound serves as an important resource for researchers studying the therapeutic potential of NSD2 modulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3031353-59-7
Applications PROTAC NSD2 Degrader
Formula C43H40N8O10
Molecular Weight 828.83
SMILES
O=C(NCCCOC1=CN=C(C=C1)NC(C2=CC=C(C=C2)CN(C3CC3)C(C4=CC=C5NC(COC5=C4)=O)=O)=O)CNC6=CC=CC7=C6C(N(C7=O)C8CCC(NC8=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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