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MS8815N

MS8815 Negative Control

MS8815N serves as a negative control for the EZH2 PROTAC degrader MS8815, designed to lack the ability to recruit the VHL E3 ligase while preserving the EZH2 binding moiety and linker structure. This compound is particularly useful in research related to triple-negative breast cancer (TNBC), providing a reliable tool for elucidating the mechanisms of PROTAC-mediated degradation in experimental settings. Its application aids in validating the specificity and effectiveness of EZH2-targeted degradation strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2855085-26-4
Applications	MS8815 Negative Control
Formula	C₇₂H₉₃N₉O₈S
Molecular Weight	1244.63
SMILES	CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(CCCCCCCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@H](C5)OCC6=CC=CC=C6)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)=O)=CC(C(NCC9=C(C=C(NC9=O)C)C)=O)=C2C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.