Fig. 1 · Structure

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MSRV-IN-1

Rhabdoviruses Inhibitor

MSRV-IN-1 is a potent inhibitor specifically targeting rhabdoviruses, including MSRV, SVCV, and IHNV. With IC50 values of 0.92 μM, 2.92 μM, and 2.78 μM respectively, it disrupts viral replication by altering the cell cycle arrest induced by the virus, creating an unfavorable environment for replication. Intraperitoneal administration at 20 mg/kg notably enhances the survival rate of largemouth bass infected with MSRV by 35.98% while effectively reducing viral loads in critical organs such as the liver, spleen, and kidney. This compound is valuable for researching rhabdovirus-related diseases in aquaculture.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1438403-50-9
Applications Rhabdoviruses Inhibitor
Formula C18H16N2O6
Molecular Weight 356.33
SMILES
OC1=C([N+]([O-])=O)C=C(CC=C)C=C1C2=CC(CC=C)=CC([N+]([O-])=O)=C2O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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